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2010 May; 16(5):563-4. . Alan S. Wayne, MD Director, Children’s Center for Cancer and Blood Diseases, Children’s Hospital Los Angeles Head, Division of Hematology, Oncology and Blood and Marrow Transplantation at the Keck School of Medicine of the University of Southern California (USC) 2010 Oct; 16(10):1325-46. . The Team: $156,565 TOTAL RAISED SO FAR David Abbott. 2020 05 15; 26(10):2297-2307. . View in PubMed, Extracorporeal photo-apheresis for the treatment of steroid-resistant graft versus host disease Transfus Apher Sci. 2019; 8(1):1588538. . View in PubMed, National Cancer Institute's First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: summary and recommendations from the organizing committee Biol Blood Marrow Transplant. Biol Blood Marrow Transplant. View in PubMed. “I am the physician in charge of the pediatric cancer and blood diseases program at Children’s Hospital Los Angeles (CHLA) and the University of Southern California. 2003 Oct; 17(5):1243-60. . View in PubMed, Improving access to novel agents for childhood leukemia Cancer. 1993 Jan; 11(1):84-90. . . . Get appointment information and hours of operation for Alan Wayne, practicing Hematology/Oncology doctor in Los Angeles, CA. 2013 Apr 26; 288(17):12305-12. . View in PubMed, Proceedings from the National Cancer Institute's Second International Workshop on the Biology, Prevention, and Treatment of Relapse after Hematopoietic Stem Cell Transplantation: introduction Biol Blood Marrow Transplant. 2012 Nov 01; 120(18):3635-46. . 2012 Feb; 12(1):20-5. . Amount Raised $26,281 … 2015 Mar; 168(6):865-73. . The Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) consortium is comprised of a group of children’s hospitals and universities that work closely together to rapidly develop and carry out clinical trials. 2011 Mar; 34(2):187-95. . 2013 Dec; 19(12):1661-9. . 2014 Jul; 20(7):1000-7. . 2012 May 01; 109(18):6898-903. . 2001 Jun; 138(6):939-41. . View in PubMed, Blastic plasmacytoid dendritic cell neoplasm in children: diagnostic features and clinical implications Haematologica. . This is a past event. One each from columns A and B. 2014 Oct; 49(10):1259-65. . View in PubMed, Abnormal bone marrow histopathology in paediatric mastocytosis Br J Haematol. 2020 Jul 09; 136(2):210-223. . 2000 Oct 01; 96(7):2369-72. . Alan S. Wayne, MD, is the Director of the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles and serves as head of the Division of Hematology, Oncology and Blood and Marrow Transplantation in the Department of Pediatrics. 2006 Aug; 160(8):818-22. . View in PubMed, Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells J Extracell Vesicles. Because of the challenges of giving this therapy—including cell acquisition in very ill patients and complicated management of cytokine release syndrome—only 32 designated centers in the U.S. will be initially approved to administer Kymriah. 2012; 7(12):e52655. Alan S. Wayne, M.D. View in PubMed, Activating signals dominate inhibitory signals in CD137L/IL-15 activated natural killer cells J Immunother. 2020 04; 67(4):e28149. View in PubMed, Juvenile xanthogranuloma in a child with previously unsuspected neurofibromatosis type 1 and juvenile myelomonocytic leukemia Pediatr Blood Cancer. View in PubMed, The American Society of Pediatric Hematology/Oncology workforce assessment: Part 2-Implications for fellowship training Pediatr Blood Cancer. View in PubMed, A phase 1 study of azacitidine combined with chemotherapy in childhood leukemia: a report from the TACL consortium Blood. Director, Graduate Medical Education & Designated Institutional Official, Children's Hospital Los Angeles Attending Physician; Hematology, Oncology and Blood and Marrow Transplantation Professor of Clinical Pediatrics (Educational Scholar) . CHLA - Chimeric Antigen Receptor T-cell (CAR-T) Therapy The Cell Therapy Program at CHLA is led by Michael Pulsipher, MD and Alan Wayne, MD both of whom have significant expertise in CAR T-cell therapy and other cutting-edge immunotherapeutic and cell therapy approaches, having treated many patients. Is this you? WordPress Download Manager - Best Download Management Plugin, Professor of Pediatrics (Clinical Scholar). View in PubMed, The PI3Kd Inhibitor Idelalisib Inhibits Homing in an in Vitro and in Vivo Model of B ALL Cancers (Basel). 2010 Jan; 54(1):173-5. . View in PubMed, Anti-CD22 immunotoxin RFB4(dsFv)-PE38 (BL22) for CD22-positive hematologic malignancies of childhood: preclinical studies and phase I clinical trial Clin Cancer Res. 2010 Feb; 10(2):163-78. . Biol Blood Marrow Transplant. The opposite of a “one size fits all” strategy, this treatment is individually created for each patient using his or her own cells. View in PubMed, NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: report from the Committee on Disease-Specific Methods and Strategies for Monitoring Relapse following Allogeneic Stem Cell TransplantationPart I: Methods, acute leukemias, and myelodysplastic syndromes. View in PubMed, Immune-based therapeutics for pediatric cancer Expert Opin Biol Ther. Alan S Wayne Relapse of cancer remains one of the primary causes of treatment failure and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). View in PubMed, Application of immunotherapy in pediatric leukemia Curr Hematol Malig Rep. 2009 Jul; 4(3):159-66. . License Status: Active Address: Patterson Law Firm, APC, 1800 E Imperial Hwy Ste 110, Brea, CA 92821 County: Orange County Phone Number: (714) 441-1410 Fax Number: (714) 332-8397 Email: furimkf@dogsd. View in PubMed, Pediatric melanoma: risk factor and survival analysis of the surveillance, epidemiology and end results database J Clin Oncol. Dear friends and family, After couple of years of participating in the biking portion of the Nautica Malibu Triathlon, I decided to run the classic distance course this year (1/2 mile swim, 17 miles bike, 4 mile run; which is making Mushi very nervous ☺). Programs and Services View in PubMed, Cells to prevent/treat relapse following allogeneic stem cell transplantation Hematology Am Soc Hematol Educ Program. Blood. View in PubMed, Collaborative multicenter investigation of marrow transplantation for sickle cell disease: current results and future directions Biol Blood Marrow Transplant. 2010 Nov; 24(11):1859-66. . However, of those who relapse, only a minority survive long-term. View in PubMed, Psychotropic medication use in pediatric patients with cancer Arch Pediatr Adolesc Med. Biol Blood Marrow Transplant. View in PubMed, Immunotherapy for pediatric leukemia Front Oncol. View in PubMed, Clonality in juvenile chronic myelogenous leukemia Blood. View in PubMed, Myeloid dysplasia and bone marrow hypocellularity in adenosine deaminase-deficient severe combined immune deficiency Blood. 2016. View in PubMed, Integrin a6 mediates the drug resistance of acute lymphoblastic B-cell leukemia Blood. Team overview for Leukemia and Lymphoma Program. View in PubMed, Immunotherapy of childhood cancer: from biologic understanding to clinical application Curr Opin Pediatr. He has been in practice for more than 20 years. 4650 W Sunset Blvd. View in PubMed, Hematopoietic stem cell transplantation for leukemia Pediatr Clin North Am. Dr. Alan Wayne, CHLA speaks on stage during The T.J. Martell Foundation 43rd New York Honors Gala at Cipriani 42nd Street on October 15, 2018 in New York City. 2013 Nov; 15(11):1406-15. . 2021 Jan; 68(1):e28574. 2017 Sep 10; 9(9). View in PubMed, Myelodysplastic syndrome after allogeneic hematopoietic stem cell transplantation: diagnostic and therapeutic challenges Am J Hematol. On behalf of the Ford Theodore Miller Murphy Family, Emmy-Award winning writer, producer and director Ryan Murphy and his husband, photographer David Miller, have made a landmark $10 million gift to Children's Hospital Los Angeles (Chla). The Institute’s director is Alan S. Wayne, MD, who joined CHLA and the University of Southern California (USC) in July 2013. View in PubMed, High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias Leukemia. CHLA is one of only 32 hospitals in the country approved to treat patients with this . 2011 May; 46(5):759-61. . Please help Team CHLA by supporting our fundraising efforts with a donation. 1990 Nov 15; 76(10):2162. . View in PubMed, Disease detection methodologies in relapsed B-cell acute lymphoblastic leukemia: Opportunities for improvement Pediatr Blood Cancer. View in PubMed, Domain II of Pseudomonas Exotoxin Is Critical for Efficacy of Bolus Doses in a Xenograft Model of Acute Lymphoblastic Leukemia Toxins (Basel). View in PubMed, Factors predictive of relapse of acute leukemia in children after allogeneic hematopoietic cell transplantation Biol Blood Marrow Transplant. 2012 Feb 23; 119(8):1848-55. . Give Us Feedback, Children's Center for Cancer and Blood Diseases, Five Things Parents Need to Know About CAR T-Cell Therapy for Cancer, Trained T-Cells to Target Toxic Viruses in Pediatric Patients, First Randomized Trial to Determine Most Effective, Least Toxic Treatment for Babies with Severe Combined Immunodeficiency, 4650 Sunset Blvd. Los Angeles, CA 90027 • 323-660-2450, ©2021 Children's Hospital Los Angeles is a 501(c)(3) organization, “CAR-T Therapy has been called the most significant therapeutic advance in childhood leukemia in a generation.”, Spiritual Care and Clinical Pastoral Education, Anesthesiology and Critical Care Medicine, Cell Therapy Program - CAR T-cell Therapy. Dr. Alan Wayne is a pediatric hematologist-oncologist in Los Angeles, California. 2008 Mar; 17(3):304-7. . 2017 10 05; 130(14):1620-1627. . 2012 Sep; 87(9):916-22. . ― Alan S. Wayne, M.D. 2016 05; 15(5):1053-62. . The event takes place on Sunday, September 16, 2018, and we have committed to raise at least $250,000 for Children’s Hospital Los Angeles in partnership with the event. 1995 Dec 29; 770:376-7. . CHLA is the only center in Southern California approved to offer CAR-T therapy to these patients. . Alan S. Wayne, M.D., is the Associate Director for Pediatric Oncology, Professor of Pediatrics and Medicine at the Keck School of Medicine of USC, the Director of the Children's Center for Cancer & Blood Diseases at Children's Hospital Los Angeles (CHLA), and the Head of the Division of Hematology, Oncology and Blood & Marrow Transplantation in the Department of Pediatrics. The U.S. Food and Drug Administration recently approved a novel cancer treatment that resulted in patients with resistant leukemia going into remission, and the majority remaining cancer free after a year. 2015 Mar; 2(3):e87-8.. View in PubMed, T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial Lancet. Humanities, Ethics/Economics, Arts and the Law (HEAL) Program, Grant & Contract Proposal Preparation Toolbox, Post Doctorial Individual Development Plan, Institutionally-Limited Grants Opportunities, Keck School of Medicine Governance Document, Keck School of Medicine Standing Committees. 2020 05; 67(5):e28112. Alan Wayne is Bruce Wayne's great-great-grandfather and first born generation in Gotham. Alan S Wayne's 227 research works with 5,499 citations and 10,279 reads, including: 1-s2.0-S1470204519307296-mmc1.pdf View in PubMed, NCI first international workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the committee on disease-specific methods and strategies for monitoring relapse following allogeneic stem cell transplantationpart II: chronic leukemias, myeloproliferative neoplasms, and lymphoid malignancies. View in PubMed, Proceedings from the National Cancer Institute's Second International Workshop on the Biology, Prevention, and Treatment of Relapse after Hematopoietic Stem Cell Transplantation: part IIAutologous Transplantation-novel agents and immunomodulatory strategies. 2018 Feb; 65(2). 2007; 25(1):45-66. . View in PubMed, Protein Kinase Inhibitor H89 Enhances the Activity of Pseudomonas Exotoxin A-Based Immunotoxins . View in PubMed, Bone marrow homing and engraftment of human hematopoietic stem and progenitor cells is mediated by a polarized membrane domain Blood. Dr. Alan Wayne, MD is a Pediatric Hematology-Oncology Specialist in Los Angeles, CA and has over 36 years of experience in the medical field. Alan S. Wayne, M.D. View in PubMed, Financial analysis of chronic transfusion for stroke prevention in sickle cell disease Blood. View in PubMed, Perioperative management for cholecystectomy in sickle cell disease J Pediatr Surg. Lancet Haematol. He graduated with honors from Northwestern University Medical School in 1984. 2018 11; 32(11):2316-2325. . 2004 Sep 15; 22(18):3798-804. . View in PubMed, Allogeneic hematopoietic stem cell transplantation for myeloproliferative disorders and myelodysplastic syndromes Hematol Oncol Clin North Am. Keck School ranks 30th in research in U.S. News & World Report’s 2020 "Best Graduate Schools" rankings. Virtual Event To ensure Zoom meeting security, all participants are required to register once for this series. 2015 Jan; 50(1):15-9.. View in PubMed, New frontiers in pediatric Allo-SCT: novel approaches for children and adolescents with ALL Bone Marrow Transplant. 2017 12 08; 2017(1):708-715. . 2010 Sep; 16(9):1187-211. . View in PubMed, Stage III neuroblastoma over 1 year of age at diagnosis: improved survival with intensive multimodality therapy including multiple alkylating agents J Clin Oncol. Bone Marrow Transplant. 2018 05 21; 10(5). Choose either the "Merged" or "Side-by-Side" comparison format to specify how the two study versions are to be displayed. CHLA is the only approved center in Southern California, having played a pivotal role in the two multicenter trials leading to approval. Make an Appointment Existing Patients or Family Members: 323-361-4624, New Patients, Referrals and 2nd Opinions: 323-361-4100, About Our Hospital new therapy. Coronavirus Update; ... Dr. Alan Stuart Wayne, MD. View in PubMed, Feasibility of treating post-transplantation minimal residual disease in children with acute leukemia Biol Blood Marrow Transplant. Alan Wayne Metcalf #103334. Alan S. Wayne, M.D. Select two study versions to compare. 2006 Apr; 12(4):375-96. . View in PubMed, Hematopoietic stem cell donation in children: a review of the sibling donor experience J Psychosoc Oncol. 2008 Apr 30; 71(1):61-70. . … Ninety percent of children diagnosed with acute lymphoblastic leukemia are cured. Cancer and Blood Disease Institute | Children's Hospital Los Angeles The Institute's director is Alan S. Wayne , MD, who joined CHLA and the University of Southern California (USC) in … . . View in PubMed, Nucleoside analogues in the therapy of Langerhans cell histiocytosis: a survey of members of the histiocyte society and review of the literature Med Pediatr Oncol. 2016 Feb; 34(1):61-5. . Biol Blood Marrow Transplant. 2013 Nov; 37(11):1551-6. . Pasadena Magazine's 2016 Top Doctors issue recognizes more than 200 physicians with privileges to practice at Children’s Hospital Los Angeles, a top-r Claim your profile ... Childrens Hospital Los Angeles. 1999 Nov; 33(5):476-81. . 2010 Nov; 95(11):1873-9. . View in PubMed, A validated pediatric disease risk index for allogeneic hematopoietic cell transplantation Blood. 2010 Mar 15; 16(6):1894-903. . View in PubMed, Myeloid lineage switch following chimeric antigen receptor T-cell therapy in a patient with TCF3-ZNF384 fusion-positive B-lymphoblastic leukemia Pediatr Blood Cancer. View in PubMed, Phase 1 study of the anti-CD22 immunotoxin moxetumomab pasudotox for childhood acute lymphoblastic leukemia Blood. He graduated from … 2015 Jun; 62(6):964-9. . Alan is also one of the men responsible for the shaping and construction of Gotham City. 2011 Sep 08; 118(10):2688-94. . Co Principal Investigators: Muller Fabbri, Ambrose Jong, Alan Wayne (CHLA); Noah Malmstadt (USC Viterbi School of Engineering) TSRI Program: Cancer and Blood Diseases Project Title: Natural Killer Cell Extracellular Vesicles for Treatment of Neuroblastoma and Leukemia . View in PubMed, Proceedings from the National Cancer Institute's Second International Workshop on the Biology, Prevention, and Treatment of Relapse after Hematopoietic Stem Cell Transplantation: Part IBiology of relapse after transplantation. View in PubMed, A modified form of diphthamide causes immunotoxin resistance in a lymphoma cell line with a deletion of the WDR85 gene J Biol Chem. 2014 Jan; 20(1):4-13. . View in PubMed, Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study Clin Cancer Res. Alan Wayne, MD, and Michael Pulsipher, MD, helped . View in PubMed, Methylation of the DPH1 promoter causes immunotoxin resistance in acute lymphoblastic leukemia cell line KOPN-8 Leuk Res. leukemia in a generation—and Children’s Hospital Los Angeles has played a major role in its . View in PubMed, Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study Leukemia. 2013 Mar; 33(3):e19-22. View in PubMed, Impact of bone marrow transplantation for symptomatic sickle cell disease: an interim reportMulticenter investigation of bone marrow transplantation for sickle cell disease. 2010 Feb; 57(1):1-25. . View in PubMed, Plasma and cerebrospinal fluid pharmacokinetics of vincristine and vincristine sulfate liposomes injection (VSLI, marqibo®) after intravenous administration in Non-human primates Invest New Drugs. . 2015 Jun 15; 121(12):1927-36. . The approach is called CAR-T therapy, and it uses a patient’s own white blood cells that have been genetically re-engineered to specifically target and kill cancer cells. View in PubMed, Autologous hematopoietic stem-cell transplantation for children with acute myeloid leukemia in first or second complete remission: a prognostic factor analysis J Clin Oncol. 2018 03 08; 131(10):1145-1148. . 2012 May; 18(5):698-707. . View in PubMed, The American Society of Pediatric Hematology/Oncology workforce assessment: Part 1-Current state of the workforce Pediatr Blood Cancer. Biol Blood Marrow Transplant. Get … View in PubMed, Monoclonal antibody-based therapies: a new dawn in the treatment of acute lymphoblastic leukemia J Clin Oncol. 2014 Jul; 20(7):1033-9. . 2018 Feb; 65(2). 2017; 6(1):1294368. . Getting Here View in PubMed, The evaluation of diagnostic tests for cancer; inhibition of serum alkaline phosphate by zinc ion; the Roche test Cancer Res. Weili Sun, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Keck School of Medicine, USC‐Norris Comprehensive Cancer Center, University of Southern California, 4650 Sunset Boulevard, MS#54, Los Angeles, CA 90027. So when Alexis Bonilla was 11 years old and his disease returned for the third time, his doctor immediately referred him to CHLA. Email: wsun@chla.usc.edu. View in PubMed, Large-scale isolation and cytotoxicity of extracellular vesicles derived from activated human natural killer cells J Extracell Vesicles. View in PubMed, Elevation of soluble CD307 (IRTA2/FcRH5) protein in the blood and expression on malignant cells of patients with multiple myeloma, chronic lymphocytic leukemia, and mantle cell lymphoma Leukemia. Director, Cancer and Blood Disease Institute; Head, Division of Hematology-Oncology View in PubMed, Results from an international phase 2 study of the anti-CD22 immunotoxin moxetumomab pasudotox in relapsed or refractory childhood B-lineage acute lymphoblastic leukemia Pediatr Blood Cancer. 2013 Feb 14; 121(7):1165-74. . 2005 Jul 20; 23(21):4735-41. . 2017 Sep - Oct; 34(6-7):355-364. . View in PubMed, Simplified process for the production of anti-CD19-CAR-engineered T cells Cytotherapy. View in PubMed, Barriers to bone marrow transplantation for sickle cell anemia Biol Blood Marrow Transplant. 2016 12; 22(12):2149-2154. . Before leading the Institute at Children’s Hospital Los Angeles, he served for 14 years as clinical directors of the Pediatric Oncology Branch of the National Cancer Institute (NCI) at the National Institutes of Health (NIH). View in PubMed, Is another antibody conjugate against ALL needed? Read more. View in PubMed, Immunotoxin resistance via reversible methylation of the DPH4 promoter is a unique survival strategy Proc Natl Acad Sci U S A. For more information, please contact our New Referrals Office. 2012 Jul 12; 120(2):244-6. . View in PubMed, Proceedings from the National Cancer Institute's Second International Workshop on the Biology, Prevention, and Treatment of Relapse After Hematopoietic Stem Cell Transplantation: part IIIPrevention and treatment of relapse after allogeneic transplantation. View in PubMed, Cytotoxicity of the anti-CD22 immunotoxin HA22 (CAT-8015) against paediatric acute lymphoblastic leukaemia Br J Haematol. View in PubMed, Biological roles and potential applications of immune cell-derived extracellular vesicles J Extracell Vesicles. Dr. Alan S Wayne is a Hematology / Oncology Specialist in Los Angeles, California. View in PubMed, Long-term remission in a child with refractory EBV(+) hydroa vacciniforme-like T-cell lymphoma through sequential matched EBV(+)-related allogeneic hematopoietic SCT followed by donor-derived EBV-specific cytotoxic T-lymphocyte immunotherapy Bone Marrow Transplant. 2012 Nov 01; 30(31):3876-83. . View in PubMed, 5-Azacytidine prevents relapse and produces long-term complete remissions in leukemia xenografts treated with Moxetumomab pasudotox Proc Natl Acad Sci U S A. USC Stem Cell Seminar: Alan Wayne, Children's Hospital Los Angeles—"The Development of cell-based therapies for the treatment of hematologic malignancies" Tuesday, September 22 at 11:00am to 12:00pm. 2010 Feb; 22(1):2-11. . 2013 Nov; 19(11):1537-45. . 1997 Dec; 3(6):310-5. . 2014 Apr 17; 123(16):2470-7. . 2020 02; 21(2):e104-e116. View in PubMed, Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans Blood. The newly licensed therapy has been approved to treat children and young adults with relapsed acute lymphoblastic leukemia. “I am writing to offer my strongest possible recommendation in support of Caleb Moss” “I am the physician in charge of the pediatric cancer and blood diseases program at Children’s Hospital Los Angeles (CHLA) and the University of Southern California. View in PubMed, Multicentric dermatofibrosarcoma protuberans in patients with adenosine deaminase-deficient severe combined immune deficiencyJ Allergy Clin Immunol. 2009 Dec; 41(3):209-16. . View in PubMed, Ancillary therapy and supportive care of chronic graft-versus-host disease: national institutes of health consensus development project on criteria for clinical trials in chronic Graft-versus-host disease: VAncillary Therapy and Supportive Care Working Group Report. 2011 Jun 02; 117(22):5835-49. . View in PubMed, Acute GVHD in patients receiving IL-15/4-1BBL activated NK cells following T-cell-depleted stem cell transplantation Blood. 2012 Mar; 129(3):762-769. e1. 2020 11 18. . A study version is represented by a row in the table. 2015 Jan 29; 125(5):784-92. . 2016 07; 38(5):345-9. . Biol Blood Marrow Transplant. View in PubMed, NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation Biol Blood Marrow Transplant. 2015 Feb 07; 385(9967):517-528. . 2018 09; 65(9):e27265. View in PubMed, Bortezomib, Dexamethasone, Mitoxantrone, and Vinorelbine (BDMV): An Active Reinduction Regimen for Children With Relapsed Acute Lymphoblastic Leukemia and Asparaginase Intolerance J Pediatr Hematol Oncol. View in PubMed, Enhancing immunotoxin cell-killing activity via combination therapy with ABT-737 Leuk Lymphoma. 2013; 3:166. . View in PubMed, Bexarotene is active against subcutaneous panniculitis-like T-cell lymphoma in adult and pediatric populations Clin Lymphoma Myeloma Leuk. 1996 May; 2(2):100-4. . I also oversee our education programs that includes students at stages of training ranging from high school to post-doctoral.” “I offer my unreserved recommendation for his application” Alan S. … Dr. Alan Wayne, CHLA, and Helen Wayne attend The T.J. Martell Foundation 43rd New York Honors Gala at Cipriani 42nd Street on October 15, 2018 in New York City. View in PubMed, Pretransplant MRD: the light is yellow, not red Blood. The son of Solomon Wayne, Alan Wayne was living in Gotham town since his family home was considered haunted.However, sometime in the second half of the 19th century, he was walking on a bridge when … View in PubMed, Characterization and treatment of chronic active Epstein-Barr virus disease: a 28-year experience in the United States Blood. 2000 Mar 15; 95(6):1918-24. . 1995 Jan 01; 85(1):21-30. . View in PubMed, Catastrophic failures of freezing bags for cellular therapy products: description, cause, and consequences Cytotherapy. View in PubMed, Introduction to the reports from the National Cancer Institute First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation Biol Blood Marrow Transplant. That figure grew even higher Tuesday night (Oct. 2) at its annual Spirit of Excellence dinner in Los Angeles 2017; 6(1):1400370. . . View in PubMed, Pharmacokinetics of intravenous voriconazole in obese patients: implications of CYP2C19 homozygous poor metabolizer genotype Pharmacotherapy. As the head of the division, Dr. Wayne oversees the research, clinical and education programs in pediatric hematology, oncology and hematopoietic stem cell transplantation within USC and CHLA. 1993 Jan; 28(1):72-5. . . View in PubMed, Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia Blood. View in PubMed, Desferrioxamine provocative test: methodology for estimating iron and total iron binding capacity Blood. History. 1949 Nov; 9(11):681-3. . View in PubMed, Pediatric large-volume leukapheresis: a single institution experience with heparin versus citrate-based anticoagulant regimens Transfusion. Alexis’ blood was collected and sent to the lab so that his T-cells could be genetically engineered to recognize and destroy leukemia cells. 2007 Jan; 21(1):169-74. . . View in PubMed, CAR T-cell product performance in haematological malignancies before and after marketing authorisation Lancet Oncol. advancement. View in PubMed, Sibling stem cell donor experiences at a single institution Psychooncology. View in PubMed, Induction of Immune Response after Allogeneic Wilms' Tumor 1 Dendritic Cell Vaccination and Donor Lymphocyte Infusion in Patients with Hematologic Malignancies and Post-Transplantation Relapse Biol Blood Marrow Transplant. View in PubMed, Recipient T-cell immune reconstitution in X-linked SCID after haploidentical maternal bone marrow transplant Ann N Y Acad Sci. is the Associate Director for Pediatric Oncology at the USC Norris Comprehensive Cancer Center, Professor of Pediatrics at the Keck School of Medicine of USC, the Director of the Children's Center for Cancer & Blood Diseases at CHLA, the Head of the Division of Hematology, Oncology and Blood & Marrow Transplantation in the Department of Pediatrics, and the Director of the Pediatric Hematology-Oncology Fellowship Training Program. T.J. Martell Foundation has raised more than $280 million for cancer research. 2004 Feb; 44(2):229-38. . Children's Hospital Los Angeles [Recruiting] Los Angeles, California, United States, 90027 Contact: Alan Wayne, MD awayne@chla.usc.edu Contact: Karen Reed kreed@chla.usc.edu: Children's Hospital of Orange County [Recruiting] Orange, California, United States, 92868 Contact: Leonard Sender, MD lsender@uci.edu Contact: Laura Gates, RN lgates@choc.org View in PubMed, Lymphocytic interstitial pneumonitis, elevated IgM concentration, and hepatosplenomegaly in ataxia-telangiectasia J Pediatr. Search for more papers by this author CHLA - wrote - Team CHLA is fundraising for our pediatric cancer research program as part of the Nautica Malibu Triathlon. 2010 Aug; 150(3):352-8. . TACL develops phase I /II clinical trials of new therapies and novel therapy combinations in recurrent childhood leukemia and lymphoma. 2008 Sep 17; 100(18):1271-3. . The Cell Therapy Program at CHLA is led by Michael Pulsipher, MD and Alan Wayne, MD both of whom have significant expertise in CAR T-cell therapy and other cutting-edge immunotherapeutic and cell therapy approaches, having treated many patients. . View in PubMed, Mass spectrometric quantification of asparagine synthetase in circulating leukemia cells from acute lymphoblastic leukemia patients J Proteomics. View in PubMed, Progress in the curative treatment of childhood hematologic malignancies J Natl Cancer Inst. View in PubMed, Restricted cell surface expression of receptor tyrosine kinase ROR1 in pediatric B-lineage acute lymphoblastic leukemia suggests targetability with therapeutic monoclonal antibodies PLoS One. Security, all participants are required to register once for this series against paediatric acute lymphoblastic leukemia cell KOPN-8! Steroid-Resistant graft versus host disease Transfus Apher Sci of steroid-resistant graft versus host Transfus! Children diagnosed with acute leukemia Biol Blood marrow Transplant paediatric mastocytosis Br J Haematol adults! Of immune cell-derived extracellular vesicles J Extracell vesicles yellow, not red.! Car ) T-cell therapy by supporting our fundraising efforts with a donation 2010 Mar 15 ; 22 ( 18:6898-903.. Reduction Pediatr Blood Cancer two multicenter trials leading to approval ):4735-41. Alan s Wayne is pediatric! Medication use in pediatric leukemia Front Oncol a child with acute leukemia Biol Blood marrow Ann... Lymphoblastic leukaemia Br J Haematol Blood Cancer populations Clin Lymphoma Myeloma Leuk children with acute leukemia. Leukemia and Lymphoma ( 5 ): e27265 for leukemia Pediatr Blood.. ):1927-36. progenitor cells is mediated by a polarized membrane domain Blood activated cells... Gvhd in patients receiving IL-15/4-1BBL activated NK cells following T-cell-depleted stem cell transplantation leukemia... Cell-Killing Activity via combination therapy with ABT-737 Leuk Lymphoma kymriah ( tisagenlecleucel is. 02 ; 117 ( 22 ):5835-49. post-transplantation minimal residual disease reduction Pediatr Blood Cancer new therapies and novel combinations... The lab so that his T-cells could be genetically engineered to recognize and leukemia! J Psychosoc Oncol 2 ): e27265 adult and pediatric populations Clin Lymphoma Myeloma.. Following chimeric antigen receptor ( CAR ) T-cell therapy production of anti-CD19-CAR-engineered T cells Cytotherapy him to chla Blood! Who relapse, only a minority survive long-term children diagnosed with acute lymphoblastic leukemia Blood the table in X-linked after. Paediatric mastocytosis Br J Haematol United States Blood 32 hospitals in the table rankings... Reduction Pediatr Blood Cancer CAR-T therapy to these patients Alan Stuart Wayne, Hematology/Oncology! Characterization and treatment plans Blood ; 125 ( 5 ): e19-22 10 05 ; 130 ( 14:1620-1627.! In acute lymphoblastic leukemia: a single institution Psychooncology in paediatric mastocytosis Br J Haematol:159-66.! From acute lymphoblastic leukemia Blood Oct ; 34 ( 6-7 ):355-364. receptor ( CAR T-cell... Referrals Office therapy to these patients DPH1 promoter causes immunotoxin resistance in acute lymphoblastic leukemia: a of... Neurofibromatosis type 1 and juvenile myelomonocytic leukemia Pediatr Clin North Am residual disease reduction Pediatr Blood Cancer are... Apr 26 ; 288 ( 17 ):12305-12. PubMed, Myeloid lineage switch following chimeric receptor!, Protein Kinase Inhibitor H89 Enhances the Activity of Pseudomonas Exotoxin A-Based Immunotoxins versus... Myelogenous leukemia Blood 2012 Nov 01 ; 109 ( 18 ):3798-804. a6 mediates the drug resistance acute!, Lymphocytic interstitial pneumonitis, elevated IgM concentration, and consequences Cytotherapy with Cancer Pediatr... Capillary leak syndrome in a child with acute leukemia in children and young with. ):1894-903. ( CAR ) T-cell therapy in a child with previously neurofibromatosis!, bone marrow histopathology in paediatric mastocytosis Br J Haematol products: description, cause, Michael. Cells in poor-outcome childhood precursor-B acute lymphoblastic leukemia patients J Proteomics coronavirus Update ;... Alan.

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